Chemotherapy
Game-Changer
for
Stage
4
Cancer
GTF (Genetically Targeted Fractionated Chemotherapy) may help patients outperform conventional chemotherapy by identifying each person’s specific tumor information and genetic profile. Watch the video below to learn more.
PROMOTIONAL VIDEO
How
to
Improve
Cancer
Results
with
GTF
Chemotherapy
A
Better
Model
for
Cancer
Treatment
The current model and approach being used by numerous cancer centers and
hospitals is the “germ theory.” This model aims to focus on destroying cancer
cells using a “one size fits all” protocol – a methodology which establishes
treatment plans based solely upon cancer type and stage. Doctors are content
that each person’s cancer is unique, thereby cannot be classified or grouped –
even for patients with “the same type and stage.”New scientific studies reveal that unlocking the genetic codes for each patient’s cancer means a more successful treatment and outcome. GTF treatment goes several steps further than the conventional chemotherapy approach. It takes advantage of the understanding that everyone’s tumor is different and provides the actual blueprint information to personalize each patient’s treatment plan. Our doctors predict this new method and approach will become the world standard within 5-7 years.
So why are cancer centers not using this approach to treatment? It is very difficult for large structured institutions and pharmaceutical companies to move quickly with the world’s modern technologies because they have so much invested in the old system. That being said, GTF treatments have already begun to save lives, while even helping some patients avoid hospice. According to patients, the best part of the treatment is that this therapy avoids most all the side effects found in conventional chemotherapy treatment so patients can feel better throughout. Our doctors have noted that when patients were tested, over 75% of them were administered the wrong treatments … No wonder so many patients are struggling with cancer!
To learn more, contact us with any questions about this new approach to chemotherapy, or watch the video below to learn about a more powerful approach to cancer.
PROMOTIONAL VIDEO
A
More
Powerful
Approach
to
Cancer
Treatment
The
Negative
Aspects
of
Traditional
Chemotherapy
During World War II, a nuclear bomb was dropped on Hiroshima. The damage was
so devastating, it resulted in the deaths of many innocent people. Without
preliminary testing and targeting, large doses of chemotherapy can wreak a
similar havoc within a cancer patient’s body. The collateral damage to healthy
cells is devastating and often worse than the cancer itself, particularly in
regard to the destruction and disabling of the immune system, which is the
body’s first and last defense against cancer.
A
Proper
Approach
to
Stage
4
Cancer
Treatment
Aggressive chemotherapy treatments involves a combination of four different
drugs called MOPP protocol, which worked quite successfully with Hodgkin’s
disease during the preliminary years of cancer research. However, as MD and
Professor Dr. Guy B. Faguet* stated, “This early success was seldom replicated
despite myriad, subsequent clinical trials launched to test a variety of
intermittent combination chemotherapy regimens in many types of cancer over the
ensuing four decades.” Regarding the traditional use of chemotherapy,Dr. Guy B.
Faguet* also stated, ”Though most patients achieve some degree of tumor
response, few survive longer as a result.”
Genetics:
The
Future
of
Cancer
Treatment
has
Arrived
Currently, the odds that a patient will respond to
any given chemotherapy
treatment are generally no better than the odds of flipping a coin.
Chemotherapy drugs have historically been tested, dosed, and incorporated into
treatment protocols based on trial-and-error approaches, resulting in a single
or a range of recommended dosages based on averages from clinical studies in
large populations.
The cancer patients who continue to receive chemotherapy drugs that they
simply don’t respond to are unknowingly suffering through devastating side
effects all while simultaneously wasting valuable time in their fight to survive
against cancer.The good news is that recent advances in pharmacogenetic research may eliminate the randomness in chemotherapy treatment. Through genetic testing, specific gene expression patterns can be identified that can better predict a patient’s drug response. These genetic indicators act to help physicians find the optimal drug or drug combination that will combat the precise tumor in a given individual with the benefit of optimal results along with greatly reduced side effects.
Research has shown that individual genetic differences in drug-metabolizing enzymes, transporters, receptors, and other factors have been linked to significant differences in drug response, thereby affecting clinical outcomes. For example, a drug in identical dosages may be toxic to a person with a slower drug metabolism, or simply ineffective in a person with a much higher drug metabolism. A positive response might only be found in those particular individuals whose metabolism is close to the general population average in which the standard dosage protocol is based.
In addition, genomic information can also be extracted from the cancer itself to determine which treatments will be most effective. Mutations of various growth regulatory genes, as well as alterations in the transcription of a large number of genes, which may lead to a tumor’s possible resistance to a treatment. Envita has been refining these techniques with great success for numerous years, and we strongly believe it will soon become the standard of care in the future.
Targeting
Chemotherapy
Via
Insulin
Receptors
Due to alterations in the mitochondria shifts toward glycolysis, cancer cells
develop the ability to produce insulin with an Insulin-like Growth Factor (IGF)
themselves. This way, a cancer cell can increase its glucose uptake and
metabolism.The ability to produce insulin makes cancer cells different from normal cells, but there is a second abnormality to note. Every cell in the body has insulin receptors on the outer surface of its membrane (about 100-100,000 receptors per healthy cell). However, cancer cells have a much higher concentration of insulin receptors than the healthy cell. Various studies have shown that the amount of insulin receptors (IR) is dramatically increased in most human breast cancers as well as both ligand-dependent malignant transformations. The high metabolic activity of the cancer actually provides delivery methods enabling the targeting of cancer cells over the healthy ones.
Fractionated
Chemotherapy
Allows
for
a
Stronger
Immune
System
Fractionated chemotherapy is a technique by which the total dose of
chemotherapy is broken into smaller amounts and then administered over a longer
period of time, rather than in a single, much larger dose. Administration in
this manner makes the drugs more tolerable to patients by greatly reducing the
devastating side effects often experienced as a result of the large doses.Additionally, cancer cells experience a longer, more sustained exposure to the toxin. For this reason, targeted chemotherapy is another method of treatment that utilizes specific agents to help the delivery of chemotherapy to precise tissues and regions of the body. When lower doses are given, your immune system is better able to respond instead of being wiped-out altogether.
In
Summary
GTF treatment allows the patient to experience all the possible benefits of
chemotherapy while tremendously reducing the imminent damage to the immune
system that is commonly the result of a more conventional administration of
these treatments.
Our Comprehensive Smart Oncology® program can
utilize targeted chemotherapy to minimize damage to the healthy cells, improve
immune system function, as well as greatly improve the quality of life for our
patients. Visit the PPMR
process to learn more about other therapies that may work for you or
contact us if you have any questions.
The
following
featured
articles
will
help
you
better
understand
Envita’s
unique
approach
to
cancer
treatment
as
well
as
provide
essential
steps
to
success:
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References:
Blue Cross Blue Evaluation. Pharmacogenomics of Cancer-Candidate Genes.
Assessment Program (2007), Vol. 22, no. 5.Weinshilboum, Richard. Review of genomics Inheritance and Drug Response. New England Journal of Medicine (2003), Vol. 348, no. 6, 529-537.
Wu, Xifeng, Gu, Jian, et al. Genetic Variations in Radiation and Chemotherapy Drug Action Pathways Predict Clinical Outcomes in Esophageal Cancer. Journal of Clinical Oncology (2006), Vol 24, No. 23, 3789-3798.
Evans, William E. and Relling, Mary V. Pharmacogenomics: Translating Functional Genomics into Rational Therapeutics. Science (1999), Vol. 286, no. 5439, 487-491.
Khew-Voon Chin, et al. Application of Expression Genomics for Predicting Treatment Response in Cancer. Therapeutic Oligonucleotides (2005), Vol 1058: 186-195.
*An expert on chronic lymphocytic leukemia, Dr. Faguet received his MD degree in Bogota, Colombia and completed his postgraduate work at the University of Texas and Ohio State University. For 28 years he conducted cancer research in Augusta, Georgia that was funded mainly by the National Cancer Institute and the Department of Veterans Affairs. He’s written 140 peer-reviewed articles, seven book chapters and two scientific books on cancer.
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